When a spool is tangled, it may or may not disrupt a print. It depends on the spool and how far down it is tangled. What is suggested you do, is that you unwind about 10 meters of the filament off the spool. Try to find the tangled portion. Once you do, untangle the section, and spool it back together. Filaments can get tangled by manufacturing defects right at the factory. This happens many times and is always a guessing game when purchasing filament. Sometimes winding machines have errors and the end result can simply slip by quality control. However, there are always work-arounds!
Take a look at ALL3DP’s solutions on this subject: Filament Spool – Tips & Tricks Against Filament Tangles | All3DP